Fish Oil Supplements Can Fight Depression

Adults with major depression without anxiety may find serious benefit from omega-3 fish oil supplements, according to a new study (J Clin Psychiatry. ePub 15 June 2010. DOI: 10.4088/JCP.10m05966blu). Researchers from McGill University recruited adult outpatients (n=432) with major depressive episode (MDE, per Mini-International Neuropsychiatric Interview) lasting at least four weeks for the double blind, randomized, controlled, eight-week, parallel-group trial; 40.3 percent of subjects were taking antidepressants at baseline. Subjects received fish oil supplements containing 1,050 mg/d of eicosapentaenoic acid (EPA) and 150 mg/d of docosahexaenoic acid (DHA) or a matched sunflower oil placebo. Primary outcome was the self-report Inventory of Depressive Symptomatology (IDS-SR30); secondary outcome was the clinician-rated Montgomery-Åsberg Depression Rating Scale (MADRS).

 

The studies major finds show that fish oils may be able to help combat depression as well or better than prescription medications.

 

 


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