Tryptophan, an essential amino acid, is the precursor to Serotonin, which is a necessary neurotransmitter responsible for transmitting nerve impulses in the brain, and inducing sleep and tranquility. Serotonin deficiencies, which are related to Tryptophan deficiencies, are well documented in cases of depression and insomnia.
Tryptophan is very important for biochemical balance of the brain, and is very helpful for those with sleep deprivation, anxiety and enhancing mood due to low Serotonin levels. It also helps in cases where Serotonin levels are low because of chemical addictions. It has been effective in appetite control, increasing pain tolerance and assisting those with jet lag.
It has been well documented that low Serotonin levels and low Tryptophan levels have been associated with depression. If depression also involves Catecholamine biochemistry, then taking Tryptophan in a regimen along with Tyrosine is recommended. Since they complete for uptake in the brain, and because Tryptophan induces sleep, it is recommended that Tryptophan be taken prior to dinner and again prior to bedtime. Tyrosine should be taken prior to breakfast and mid morning as well.
L-theanine creates a sense of relaxation via at least two different mechanisms. First, this amino acid directly stimulates the production of alpha brain waves, creating a state of deep relaxation and mental alertness. Second, L-theanine is involved in the formation of the inhibitory neurotransmitter, gamma amino butyric acid (GABA). GABA influences the levels of two other neurotransmitters, dopamine and serotonin, producing the relaxation effect.
Additional human clinical research suggests that L-theanine may have application in improving the quality of sleep, diminishing normal symptoms of premenstrual syndrome (PMS), improving learning performance, heightening mental acuity, promoting concentration, reducing negative side effects of caffeine and supporting the immune system.
(GABA) is an amino acid found mainly in the human brain and eyes. It is considered an inhibitory neurotransmitter, which means it regulates brain and nerve cell activity by inhibiting the number of neurons firing in the brain. GABA is referred to as the “brain’s natural calming agent”, by inhibiting over-stimulation of the brain, GABA may help promote relaxation and ease nervous tension. GABA is also helpful in promoting sleep for those who have difficulty sleeping.
Kava Kava (Piper methysticum), is a member of the pepper family and has widely been used by South Pacific societies for more than three thousand years.
Its primary uses in the United States and Europe, are as an anti-depressant, stress reliever and muscle relaxant. Kava kava also is gaining popularity as a sleep aid. In Europe, Kava kava is being used as a natural alternative to Prozac, Valium and Xanax. Several European countries have approved kava kava for the treatment of anxiety, depression, insomnia and restlessness on the basis of extensive pharmacological data and positive results in clinical trials.
Melatonin is a hormone produced naturally in the pineal gland at the base of the brain. It is important in regulating sleep, and may play a role in maintaining circadian rhythm, the body’s natural time clock. Natural melatonin production decreases with age, and the decrease is associated with some sleep disorders, particularly in the elderly.
Studies suggest that supplements can hasten sleep and ease jet lag, without the hazards or side effects of prescription sleeping pills.
Melatonin may have many other uses and has been reported to make people feel better, strengthen the immune system, and reduce free radicals in the body.
Current research is exploring melatonin’s effect as an anti-oxidant, immno-modulator in cancer, delayed sleep-phase disorders, and more.